Optimization-based framework for inferring and testing hypothesized metabolic objective functions
نویسندگان
چکیده
منابع مشابه
Optimization-based framework for inferring and testing hypothesized metabolic objective functions.
An optimization-based framework is introduced for testing whether experimental flux data are consistent with different hypothesized objective functions. Specifically, we examine whether the maximization of a weighted combination of fluxes can explain a set of observed experimental data. Coefficients of importance (CoIs) are identified that quantify the fraction of the additive contribution of a...
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ژورنال
عنوان ژورنال: Biotechnology and Bioengineering
سال: 2003
ISSN: 0006-3592,1097-0290
DOI: 10.1002/bit.10617